A mini review: endophytic bacteria from plants and their potential to produce bioactive compounds for veterinary applications

Wahyu Eka Sari, Henni Vanda, Muhammad Hambal, Baidillah Zulkifli, Rumi Sahara Zamzami, Azhari Azhari, Annisa Nurul Qomariah, Wenny Novita Sari

Abstract


Infectious diseases caused by microorganisms, both humans and animals, are still a problem in Indonesia. The problem of bacterial resistance to antibiotics has an impact on increasing morbidity, mortality, and health care. The problem of bacterial resistance to antibiotics, which can threaten human health, has also been found in livestock. This situation has led many researchers to search for new bioactive compounds as alternative antibiotic candidates to fight multidrug-resistant bacteria such as Mycobacterium tuberculosis, Staphylococcus spp., and Streptococcus spp. This study aimed to discuss and determine the development of endophytic bacteria isolated from several plants so we can know the role of endophytic bacteria in producing bioactive compounds, especially for application in veterinary medicine. Endophytic bacteria provide great potential to produce various new bioactive compounds obtained from secondary metabolite compounds from their host. Plants are one of the hosts for endophytic bacteria. Bioactive compounds from endophytic bacteria are widely used in health and veterinary applications as antibacterial, antiviral, anti-inflammatory, and antioxidant. This shows that endophytic bacteria can be a promising source of new antibiotics to overcome the problem of pathogenic bacterial resistance and disease in the world of animal health, which also threatens human health. This review discusses aspects of the phytochemistry of endophytic bacteria producing bioactive compounds and its application in veterinary medicine.


Keywords


Antibacterial, bioactive compounds, endophytic bacteria, infectious diseases, veterinary medicine

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References


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DOI: https://doi.org/10.21157/ijtvbr.v8i1.32779

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