The effect of natural Zeolite (Ag-Zeolite) modified with silver against the inhibition of Candida albicans

Catur SEPTOMMY; Nikmatus SA’ADAH; Binti MU’AROFAH

doi:10.24815/jds.v5i2.20013

The effect of natural Zeolite (Ag-Zeolite) modified with silver against the inhibition of Candida albicans

Catur SEPTOMMY, Nikmatus SA’ADAH, Binti MU’AROFAH

Abstract

Candida albicans is a commensal microorganism or normal flora in the mouth, and about 20-75% is found in the general population without causing symptoms (Candida carriers). C. albicans is a primer agent that cause oral candidiasis. Silver modified natural Zeolite has potential antifungals. This research aimed to know the effect of silver modified natural Zeolite (Ag-Zeolite) on the C. albicans growth. Antifungals were treated through a good diffusion test. Antifungals agents were divided into four groups. They were 30 mg with 0.025 M (AgNO3), 0.05 M (AgNO3), 0.1 M (AgNO3) modified natural zeolite, and unmodified natural zeolite. Each group has treated into four times well diffusion tests. This research showed that 0.1 M (AgNO3) modified natural Zeolite has the highest inhibition. ANOVA test showed the average diameter of inhibition was significant in 0,004 (p<0,05). Each group has different average diameter inhibition. In conclusion, the active natural Zeolite with silver modification can inhibit the growth of C. albicans better than natural Zeolite without silver modification

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DOI: https://doi.org/10.24815/jds.v5i2.20013