The potential of high molecular chitosan nanohydroxyapatite as an irrigant in improving fracture resistance after root canal treatment (In Vitro)

Abstract

ABSTRACT Teeth after root canal treatment are at a higher risk of fracture than vital teeth. After root canal
treatment, the causes of tooth fracture are multifactorial, both iatrogenic and non iatrogenic. One of them is
irrigants, although very useful for disinfection. Irrigants are known to change the chemical components and
structure of the root canal surface dentin by modifying the proportion of calcium and phosphate minerals. This
research is an experimental laboratory study with a post-test-only group research design to analyze the effect of
irrigating solutions of nanohydroxyapatite, high molecular chitosan, NaOCl, and EDTA with their appropriate
combination for the test group on the fracture resistance of teeth after root canal treatment. Root canal treatment was
performed on 24 mandibular premolars, with the group I; irrigating solution of nanohydroxyapatite, group II;
irrigation of nanohydroxyapatite solution with the addition of 0.2% chitosan, group III; irrigation with 2.5% NaOCl
solution and 0.2% chitosan solution, group IV; irrigation solution of 2.5% NaOCl and 17% EDTA. ANOVA test
showed a significant difference in fracture resistance (p<0.05) between each group. The highest average fracture
resistance was seen in group II, namely the irrigation group using a solution of nanohydroxyapatite with the
addition of 0.2% chitosan, which was 363.644 ± 10,896 N. fracture after root canal treatment.
KEYWORDS: nanohydroxyapatite, irrigation solution, fracture resistance