Diffusion of calcium ions in one-third of root canals after administration of high molecular Chitosan nanohydroxyapatite medicament (In Vitro)

Abstract

ABSTRACT Calcium hydroxide is currently the gold standard medicament. Still, it has the disadvantage of leaving
a residue on the surface of the root canal wall. Hence, it can interfere with the setting time and adhesion of the sealer
material to the root canal wall. This study aims to determine the ability of calcium ion diffusion in one-third of the
root canal after administration of nanohydroxyapatite medicament with a different vehicle than calcium hydroxide.
This study used 24 mandibular premolars extracted, decorated, and prepared, then grouped into four treatment
groups. Based on the paired T-test, the study results showed no significant effect of calcium ion diffusion in group B
(p = 0.739) on the 7
th
and 14
th
days. The ANOVA test results showed no significant difference in calcium ion
diffusion between groups A, B, and C. on the 7
th
day of testing (p=0.773) and the 14
th
day (p=0.661). In conclusion,
there was no effect and difference in the diffusion of calcium ions in the apical third after administration of
medicament nanohydroxyapatite vehicle bidisstilled water and nanohydroxyapatite vehicle nanochitosan compared to
calcium hydroxide on the 7
th
and 14
th
day
KEYWORDS: diffusion, calcium hydroxide, ion calcium, nanohydroxyapatite, nano chitosan, vehicle