POTENSI ANTIBAKTERI EKSTRAK JAHE (Zingiber officinale Roscoe) TERHADAP Porphyromonas gingivalis SECARA IN VITRO

Abstract

Abstract
Chronic periodontitis is the most common periodontal disease occurs in people with prevalence of
96.58% and usually occurs at the age of 35 years and over. The main cause of chronic periodontitis is
accumulation of plaque and bacteria. The most dominant bacteria in chronic periodontitis is
Porphyromonas gingivalis. Ginger (Zingiber officinale Roscoe) is a spice plant that is widely used by
the public, contain secondary metabolites such as flavonoids, terpenoids, phenols, and essential oil
which is antibacterial. This study aim was to determined the ginger’s extract (Zingiber officinale
Roscoe) antibacterial potency against Porphyoromonas gingivalis with various concentrations are
6.25%, 12.5%, 25%, 50%, and 100%. Antibacterial potency which test done by placing a paper discs
that has been dipped in the test group with 5 concentration and the placed on the surface of the MHA
medium (Mueller Hilton Agar) which had been grown Porphyromonas gingivalis, and incubated for 24
hours at a temperature of 37 0C in an anaerobic atmosphere. Furthermore, inhibition zones were
calculated using calipers. Data were analyzed by one way ANOVA test which showed that the extract
of ginger (Zingiber officinale Roscoe) can inhibit Porphyromonas gingivalis with probability (P<0.05).
Conclusion the extract of ginger (Zingiber officinale Roscoe) cold inhibit the growth of
Porphyromonas gingivalis at 6,25% concentration of extract with average of inhibition zone 10,6 mm
that categorized weak.
Keywords: Ginger, Porphyromonas gingivalis, Chronic Periodontitis