Isolation and Identificationof Octadecane-3-on Compound From Ethyl Acetate Fraction of Momordica balsamina L. Leaves

Emma Julien Pongoh*, Rymond Jusuf Rumampuk, Vlagia Indira Paat, Stefan Marco Rumengan, Julieta Soputan

Abstract


Momordica balsamina L. is a wild plant that generally grows in moist soil and gets a lot of sunlight. The leaves and fruit are reported to have various medicinal and nutritional properties.  This study aimed to isolate and identify the compounds contained in the ethyl acetate fraction in Momordica balsamina L The isolation stage was carried out by the maceration method and the separation and purification of the compounds using gravity column chromatography methods to obtain isolate fraction F1.6.2 with a sample weight of 2.4 mg. Identification of compounds using proton nuclear magnetic resonance (1H-NMR) and carbon nuclear magnetic resonance (13C-NMR) spectroscopy techniques. The proposed identified compound is octadecan-3-one or 3-octadecanone with the molecular formula C18H36O

Keywords


pare hutan, octadecane, ethyl acetate

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References


Adamu, H.M., Ushie, O.A. Ogah, E., Longbap, N., Dawud, A.U. 2015. Phytochemical Screening and Antimicrobial Activities Of The Leaf Extracts Of Momordica Balsamina. Ewemen Journal of Microbial Research 2015, 1(1): 16-19.

Faujdar, S., Nain, S., Kalia, A.N. 2013. Antioxidant activity and Estimation of Total Phenolic content of Momordica balsamina. International Journal of Advanced Research (2013), Volume 2, Issue 2, 233-238.

Kabir, N., Umar, I. A., Dama, H. A., James, D. B., Inuwa, H. M. 2021. Isolation and Structural Elucidation of Novel Antidiabetic Compounds from Leaves of Momordica balsamina Linn and Leptadenia hastata (Pers) Decne. Iranian Journal of Pharmaceutical Research: IJPR, 20(2), 390.

Karumi Y, Onyeyili P.A, Ogugbuaja V.O. 2004. Identification of Active Principles of M. balsamina (Balsam Apple) Leaf Extract. Department of Biochemistry College of Medical Science University of Maiduguri, Nigeria.

Mabasa X.E, Mathomu L.M, Madala N.E, Musie E.M, Sigidi M.T. 2021. Molecular Spectroscopic (FTIR and UV-Vis) and Hyphenated Chromatographic (UHPLC-qTOF-MS) Analysis and In Vitro Bioactivities of the Momordica balsamina Leaf Extract. Biochemistry Research International Volume 2021.

Mshelia, Hamman, S., Karumi, Y, Dibal, N.I. 2017. Therapeutic Effect Of Momorica Balsamina Leaf Extract On Ethanol-Induced Gastric Ulcer In Wistar Rats. Annals of Research Hospitals.

Rahelivao, M.P., Lukben T., Gruner, M., Kataeva, O., Ralambondrahety, R., Andriamanantoanina, H., Checinski, M.P., Bauer, I., Knolker, H. 2017. Isolation and structure elucidation of natural products of three soft corals and a sponge from the coast of Madagascar. The Royal Society of Chemistry. Org. Biomol Chem, 2017, 15 2593-2608.

Thakur, G.S, Bag, M., Sanodiya, B.S, Bhadauriya, P., Debnath, M., Prasas, G.B.K.S, Bisen, P.S. 2009. Momordica Balsamina : A Medical and Neutraceutical Plant For Health Care Management. Current Pharmaceutical Biotechnology, 10, 667-682.




DOI: https://doi.org/10.24815/jipi.v8i1.37717

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