Histopathologic Features of Trachea and Lungs in Chickens with Chronic Respiratory Disease

Aiza Annisa; Darmawi Darmawi; Etriwati Etriwati; Ummu Balqis; M. Nur Salim; Nazaruddin Nazaruddin; Dwinna Aliza; Siti Aisyah; Awaluddin Awaluddin; Denny Irmawati Hasan; Muslim Akmal; T. Zahrial Helmi; Nuzul Asmilia

doi:10.21157/j.med.vet..v18i1.37429

Histopathologic Features of Trachea and Lungs in Chickens with Chronic Respiratory Disease

Aiza Annisa, Darmawi Darmawi, Etriwati Etriwati, Ummu Balqis, M. Nur Salim, Nazaruddin Nazaruddin, Dwinna Aliza, Siti Aisyah, Awaluddin Awaluddin, Denny Irmawati Hasan, Muslim Akmal, T. Zahrial Helmi, Nuzul Asmilia

Abstract

The purpose of this case study is to determine the changes that exist in chickens infected with Chronic Respiratory disease (CRD). A broiler male chicken aged ± 40 days was found dead in a chicken basket at Ulee Kareng chicken slaughterhouse in a state of feather loss and feces attached to cloaca, on January 6^th, 2023. The chicken was brought to pathology laboratory of Faculty of Veterinary Medicine, Universitas Syiah Kuala for necropsy and organ collection. Organs associated with CRD cases were trachea and lungs and histopathological preparations were carried out, stained with Haematoxylin Eosin, and observed under a microscope. The results of histopathological examination showed hemorrhage and hyperplasia of the tracheal epithelium. Hemorrhage was caused by edema which causes increased vascular permeability and epithelial cell hyperplasia occured due to the body's response to infection or inflammation. In the lungs there was bleeding due to damage to the blood vessel wall which caused increased vascular permeability, so that fluid and blood plasma come out of the blood vessels. Fibrinogen then underwent polymerization which resulted in fibrinous thrombi. Congestion happened as the result of fluid accumulation in a location that occured in a passive process so the fluid failed to escape. Because of the accumulation of fluid (congestion), the blood supply to the lung tissue is interrupted, resulting in several points of necrosis in the lungs.

Keywords

Chronic Respiratory Disease; broiler chicken; poultry disease

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References

Abbas, S. S., Almayahi, W. M., Alfufaei, I. A. dan Alwan, N. A. (2023). Physiological and histopathological study of chronic respiratory disease infected chickens in basrah city. Journal of Survey in Fisheries Sciences, 10(3S):2598-2608.

Adelman, J. S., Moyers, S. C., Farine, D. R. dan Hawley, D. M. (2015). Feeder use predicts bothacquisition and transmission of a contagious pathogen in a North Amercan songbird. Proc. R. Soc. B. 282(1): 14-29.

Alrufaei, I. A., & Alwan, N. A. (2023). Physiological and histopathological study of chronic respiratory disease infected chickens in basrah city. Journal of Survey in Fisheries Sciences, 10(3S), 2598-2608.

Amelia, N. K. S., Adi, A. A. A. M. dan Winaya, I. B. O. (2023). Viroterapi dengan virus newcastle disease memperbaiki gambaran histopatologi paru-paru tikus model fibrosarkoma. Buletin Veterinner Udayana, 15(6): 1035-1042.

Arachchige, S. N. K., Underwood, G. J., Andrews, D. M., Abeykoon, A. H., Wawegama, N. K., dan Browning, G. F. (2022). Measures of tracheal lesions are more discriminatory and reproducible indications of chronic respiratory disease caused by Mycoplasma gallisepticum in poultry. Avian Pathology, 51(6), 550-560.

Balqis, U., Muslina, Hambal, M., Athaillah, F., Muttaqien, Azhar, Ismail, Rastina, Eliawardani, Harris, A., Hamzah, A., Vanda, H. dan Darmawi. (2017). Perubahan histopatologi sel-sel telur dalam uterus Ascaridia galli setelah dibarikan ekstrak biji Veitchia merrillii. Traditional Medicine Journal, 22(3): 139-145.

Brar, R. S., Leishangtem, G. D., Gadhave, P. D., Singh, N. D., Banga, H. S. dan Sodhi, S. (2017). Histopathological and immunohistochemical studies on cases of chronic respiratory disease in poultry. Indian J. Vet. Pathol, 41(3): 232-234.

Diyantoro, D. dan Pribadi, E.S. (2017). Analisis faktor penularan mycoplasma gallisepticum pada peternakan ayam petelur komersial dengan metode analytical hierarchy process (analysis of mycoplasma gallisepticum infection factors in commercial layer chicken farm using analytical hierarchy process). Journal of Vocational Health Studies, 1 (2); 44-49.

Goljan, E.F. (2014). Rapid Review Pathology Fourth Edition. Elsevier Saunders, Philadelphia. Pp. 296.

Haryo, A. dan Enola, J. (2019). Pemeriksaan histopatologi rutin pada ayam ras dengan suspect soryza (stress related disease). Veterinary Biomedical and Clinical Journal, 1(2):8-14.

Ilaya Bharathi, D., Ravikumar, R., dan Jothilakshmi, M. (2017). Management of chronic respiratory disease (CRD) outbreak in an organized native chicken farm. Veterinary Pathology, 41(4), 277-282.

Kamaruzaman, I. N. A., Ng, K. Y., Hamdan, R. H., Shaharulnizim, N., Zalati, C. W. S. C. W., Mohamed, M., Nordin, M. L., Rajdi, N. Z. I. M., Abu-Bakar, L., dan Reduan, M. F. H. (2021). Complex chronic respiratory disease concurrent with coccidiosis in broiler chickens in Malaysia: A case report. Journal of Advanced Veterinary and Animal Research, 8(4), 576–580.

Manimaran, K., Mishra, A., Hemalatha, S., Karthik, K. dan Genesan, P. I. (2019). Detectionof mycoplasma gallisepticum infectionin chickens from tamil nadu state of india. Indian. J. Anim. Res, 53(1): 115-118.

Mappa, N., Rachmawati, dan Nurfadillah. (2022). Analisis resiko usaha ayam potong mandiri dan alternative penanggulangannya. Jurnal Sosial Ekonomi Pertanian dan Agribisnis. 2(1): 43-52.

Mayer, J. and T.M. Donnelly. (2013). Clinical Veterinary Advisor, Bird and Exotic Pets. Elsevier: Missouri.

Mukhtar, M., Anwar, M.I., Awais, M.M., Bhatti, N. dan Hussain, Z., (2012). Pathogenicity and effect of exogenous antibodies on the viability of Mycoplasma gallisepticum in chicken embryos. Pakistan Journal of Life Social Science, 10 (1): 13-17.

Prezotto, C.F., Marin, S.Y., Araujo, T.S., Barbosa, F.O., Barrios, P.R., Gomes, A.M., Peconick, A.P., Resende, M., Sousa, R.V. and Martins, N.R.S. (2016). Experimental coinfection of chicken anemia virus and Mycoplasma gallisepticum vaccine strains in broiler chicks. Brazilian Journal of Poultry Science, 18 (3): 475-480.

Rajkumar, S., Reddy, M. R., dan Somvanshi, R. (2017). Molecular detection and pathology of spontaneous cases of chronic respiratory disease in chicken. Indian Journal of Veterinary Pathology, 41(4):277-282.

Sari, L.P., Erina, E., dan Darniati, D. (2017). Isolasi Escherichia coli dan Salmonella sp. pada telur ayam kampung yang gagal menetas di laboratorium lapangan peternakan Universitas Syiah Kuala. Jurnal Ilmiah Mahasiswa Veteriner. 1(3): 513-520.

Widianingrum, D. C., Prakoso, S. A., Rohma, M. R., Hunafah, M. F., Iqbal, M., dan Yusantoro, D. (2022). Penyakit Chronic Respiratory Disease (CRD): Etiologi, Epidemiologi, Patogenesis, Gejala Klinis, Diagnosis, Pengobatan dan Pencegahan. Jurnal Sain Veteriner, 40(2): 221-224.

Yilmaz, F., Tlmurkaan, N., Kiliç, A., Kalender, H., and Kilinç, Ü. (2011). Detection of mycoplasma synoviae and mg in chickens by immunohistochemical, pcr, and culture methods. Rev Med Vet. 162: 79–86.

DOI: https://doi.org/10.21157/j.med.vet..v18i1.37429