The Effect of Turmeric Extract (Curcuma longa l.) As a Potential Anthelmintic on Reducing Endoparasites in Naturally-Infected Sheep
Abstract
ABSTRACT. Turmeric extract (Curcuma longa L.) has the potential to be a natural anthelmintic and alternative to commercial deworming drugs for naturally-infected local sheep. A completely randomized design was used to compare the effect of 5 different oral treatments of turmeric extract tablets at 0 (TET-0), 200 mg (TET-200), 400 mg (TET-400), 800 mg (TET-800), and commercial Oxfendazole 225mg (Oxfen-225) on reducing endoparasites (fecal egg counts, FEC) of naturally-infected local yearling ewes at day-0 (before treatments), day-7, day-14, and day-21 (after treatments) using 4 replicates (n = 4). At day-0, all experimental ewes were naturally infected by FEC Strongyles nematode ranging from 85.0 ± 32.8 to 638 ± 230 eggs/g. Meanwhile, FEC Fasciola spp. and Paramphistomum spp. (Trematode), Monieza spp. (Cestode), dan Eimeria spp. (coccidia) were found a little in a small number of ewes. Therefore, further analysis focused on FEC Strongyles. On day-7, only Oxfen-225 and TET-800 treatments reduced (P<0.05) FEC Strongyles by 100% and 64%, respectively. There was no difference (P>0.05) in the increased or reduced percentages of FEC Strongyles infections among group treatments during day-14 and day-21 although only Oxfen-225 treatment showed a constant decrease. It seems that orally administering turmeric extract tablet at 800 mg have the potential to reduce FEC Strongyles in sheep by 64% although its anthelmintic potential is still weaker than commercial oxfendazole 225 mg.
(Pengaruh Ekstrak Kunyit (Curcuma longa L.) sebagai Antelmintik terhadap Penurunan Endoparasit pada Domba yang Terinfeksi secara Alami)
Keywords
Full Text:
PDFReferences
Afrin, F., Chowdhury, M.M.R., Saha, S.S., Rahman, L., Khan, Y.A., Asgar, M.A., Islam, M.K., 2016. Efficacy of curcumin against gastro-intestinal parasites in goat. Eur. J. Pharm. Med. Res. 3(8):158-165.
AOAC. 2005. Animal Feed (Chapter 4). Official Methods of Analysis of AOAC International. In: Horwitz W, GW Latimer and NJ Wendt Thiex (Chapter Ed.):AOAC International, Suite 500, 481 North Frederick Avenue, Gaithersburg, Maryland.
Cervantes-Valencia, M.E., Alcalá-Canto, Y,. Sumano-Lopez, H., Ducoing-Watty, A.M., Gutierrez-Olvera, L., 2016. Effects of Curcuma longa dietary inclusion against Eimeria spp. in naturally-infected lambs. Small Ruminant Res. 136:27-35. DOI:10.1016/j.smallrumres.2015.12.035.
Dorny, P., Batubara, A., Iskander, M., Pandey, VS., 1996. Helminth infections of sheep in North Sumatra, Indonesia. Vet. Parasitol. 61(3):353-358. DOI:10.1016/0304-4017(95)00826-8.
Indonesia Statistics Center. 2010. Human population census 2010 result. Indonesia Statistics Centre, Jakarta.
Ishii, T, Matsuura, H., Kaya, K., Vairappan, C.S., 2011. A new bisabolane-type sesquiterpenoid from Curcuma domestica. Biochem. Syst. Ecol. 39(4-6):864-867. DOI: 10.1016/j.bse.2011.05.011
Lee, J, Jung, Y., Shin, J-H., Kim, H.K., Moon, B.C., Ryu, D.H., Hwang, G-S., 2014. Secondary Metabolite Profiling of Curcuma Species Grown at Different Locations Using GC/TOF and UPLC/Q-TOF MS. Molecules. 19(7):9535-9551. DOI: 10.3390/molecules19079535
Nasai, N.B., Abba, Y., Abdullah, F.F.J., Marimuthu, M., Tijjani, A., Sadiq, M.A., Mohammed, K., Chung, E.L.T., Omar, M.A.B., 2016. In vitro larvidical effects of ethanolic of Curcuma Linn on Haemonchus larvae stage. Vet. World. 9(4):417-420. DOI: 10.14202/vetworld.2016.417-420
Nieuwhof, G., Bishop, S., 2005. Costs of the major endemic diseases of sheep in Great Britain and the potential benefits of reduction in disease impact. Anim. Sci. 81(1): 23-29. DOI: 10.1079/ASC41010023
Pandey, J., Mishra, S., Jaiswal, K., 2018. In vitro evaluation of the anthelmintic activity of rhizome extracts of Curcuma Longa (Linn.). Asian J. Pharm. Clin. Res. 11(12):425-428.
Partoutomo, S., 2004. Parasite control by utilizing genetic host resistance. Wartazoa. 14(2):160-172.
Ramdani, D., Budinuryanto, D.C., Mayasari, N., 2020. The effect of paddy straw and concentrate containing green tea dust on performance and nutrients digestibility in feedlot lambs. Turk. J. Vet. Anim. Sci. 44(3):668-674. DOI: 10.3906/vet-1909-10
Roepstorff, A., Nansen, P., 1998. Epidemiology, diagnosis, and control of helminth parasites of swine. FAO Animal Health Manual, Rome.
Ullah, R., Rehman, A., Zafeer, M.F., Rehman, L., Khan, Y.A., Khan, M.A.H., Khan, S.N., Khan, A.U., Abidi, S.M.A., 2017. Anthelmintic potential of thymoqulnone and curcumin on Fasciola Gigantica. PLoS One. 12(2):e0171267. DOI: 10.1371/journal.pone.0171267
Vadlejch, J., Petrtýl, M., Zaichenko, I., Čadková, Z., Jankovská, I., Langrová, I., Moravec, M., 2011. Which McMaster egg counting technique is the most reliable. Parasitol. Res. 109:1387-1394. DOI: 10.1007/s00436-011-2385-5.
DOI: https://doi.org/10.17969/agripet.v21i1.17791
Article Metrics
Abstract view : 0 timesPDF - 0 times
Refbacks
- There are currently no refbacks.
Copyright (c) 2021 Jurnal Agripet
License URL: http://www.jurnal.unsyiah.ac.id/agripet/about/submissions#copyrightNotice
Copyright© 2000-2024 | ISSN: 1411-4623 | EISSN: 2460-4534
Jurnal Agripet is licensed under a Creative Commons Attribution 4.0 International License.
Published by:
Animal Husbandry Department, The Faculty of Agriculture, Universitas Syiah Kuala
associated with Animal Scientist's Society of Indonesia (HILPI).
Jl. Tgk. Hasan Krueng Kalee No. 3, Kopelma Darussalam,
Banda Aceh, 23111, Indonesia.
Phone: +62-81383736633
Email: jurnalagripet@usk.ac.id
Online Submissions & Guidelines | Editorial Policies | Contact | Statistics | Indexing | Citations