Potential of Jatropha Curcas Seed Extract Linimentum as A Therapeutic for Scabies in Goats

Nur Saidah Said, Marsudi Marsudi, Deka Uli Fahrodi

Abstract


This study aimed to evaluate the potential of Jatropha curcas seed extract liniment (JSE) as a therapeutic agent for scabies in goats. The experiment involved 20 adult goats (12–15 months old) divided into five treatment groups: P0 (negative control), P1 (positive control), P2 (10% JSE), P3 (20% JSE), and P4 (40% JSE). Each treatment group consisted of four replicates, with one goat per replicate. The JSE preparation was applied topically to the affected skin twice daily (morning and evening) for 14 days. Data were collected on days 0, 3, 7, 10, and 14, assessing clinical parameters such as alopecia, skin thickening, scab formation, and scabies recovery time. The results indicated that the 40% JSE treatment (P4) exhibited superior efficacy compared to lower concentrations, yielding outcomes comparable to the positive control (ppt sulfur liniment), a widely used scabies treatment.

Keywords


goat; jatropha curcas; linimentum; medicine; scabies

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References


Athandau, D.R., Laut, M.M., Utami, T., 2023. Studi literatur uji aktivitas ekstrak etanol daun anting-anting (Acalypha indica Linn.) terhadap penyembuhan luka bakar pada hewan coba. Jurnal Veteriner Nusantara, 6(2), 350-363. https://doi.org/10.35508/jvn.v6i2.5663

Cahyani, A.P., Primawati, P., Widiarso, B.P., Mubarokah, W.W., 2021. Aktivitas salep ekstrak daun sirsak (Annona Muricatal.) dalam penyembuhan scabies pada kambing secara in vivo. Jurnal Pengembangan Penyuluhan Pertanian, 18(33), 32-40. https://doi.org/10.36626/jppp.v18i33.613

Hussain, A.H., Hussain, N.M., Ali, S., 2021. An overview of the epidemiology, transmission, pathogenesis and treatment of scabies. The British Student Doctor Journal, 5(1), 54-62 https://doi.org/10.18573/bsdj.162

Indriyani, N.R., Djamaludin, A., Helmiawati, Y., 2021. Pembuatan sediaan obat gosok (Linimentum) dari bahan kelapa (Cocos nucifera L.) dan ekstrak daun jotang kuda (Synedrella nodiflora). Journal of Holistic Health Sciences, 5(1), 57-61. https://doi.org/10.51873/jhhs.v5i1.148

Kumalasari, M.L.F., Andiarna, F., 2020. Uji fitokimia ekstrak etanol daun kemangi (Ocimum basilicum L). Indonesia Journal for Health Sciences, 4(1), 39-44. https://doi.org/10.24269/ijhs.v4i1.2279

Martínez, G., Mijares, M.R., De Sanctis, J.B., 2019. Effects of flavonoids and its derivatives on immune cell responses. recent patents on inflammation and allergy drug discovery, 13(2), 84-104. https://doi.org/10.2174/1872213x13666190426164124

Mursyid, T.A., Ginting, N., Patriani, P., Anwar, 2022. The Effectiveness of eco enzymes to suppress the development of sarcoptes scabiei mites in vitro. Jurnal Peternakan Integratif, 10(1), 61-70. https://doi.org/10.32734/jpi.v10i01.8691

Nega, G.M.M., Yatmasari, E., Tjandra, A.S.A., 2022. Literature study: effectiveness of scabies treatment using natural ingredients. Jurnal Ilmiah Kedokteran Wijaya Kusuma, 11(2), 138-144. http://dx.doi.org/10.30742/jikw.v11i2.1294

Nilan H., C., Monalisa S., L., Inayah, A., Handayani, D., 2019. Ekstraksi daun sirih, batang sereh dan bawang merah untuk produksi pestisida organik. Jurnal Inovasi Teknik Kimia, 4(1), 21-25. http://dx.doi.org/10.31942/inteka.v4i1.2682

Osti, M.H., Sokana, O., Lake, S., Whitfeld, M.J., Boara, D., Nasi, T., Dauer, S., Marks, M., Romani, L., Kaldor, J.M., Steer, A.C., Engelman, D., 2022. The body distribution of scabies skin lesions. JEADV Clinical Practice, 1(2), 111-121. https://doi.org/10.1002/jvc2.26

Rahman, S., Toepak, E.P., Angga, S.C., Ysrafil, Y., 2023. Uji aktivitas antioksidan dan sitotoksik ekstrak daun jarak pagar (Jatropha curcas). Jurnal SAGO Gizi dan Kesehatan, 4(2), 237-246. https://doi.org/10.30867/gikes.v4i2.1175

Raoof, G.F.A., Mohamed, A.W.L., 2020. Exploring the antiparasitic activity of medicinal plants. Universal Journal of Pharmaceutical Research, 5(4), 71-75. https://doi.org/10.22270/ujpr.v5i4.442

Risyani, R., Jamaluddin, A.W., Mursalim, M.F., 2018. Aktivitas ekstrak daun sirsak (Annona Muricata L.) secara in vivo terhadap scabies pada kambing kacang (Capra hircus). Jurnal Ilmiah As-Syifaa, 10(2), 180-190. https://doi.org/10.33096/jifa.v10i2.353

Rizkia, B., Meliandari, D., Hajrin, W., 2022. The Comparison of total phenolic in the extract of Brucea javanica L. Merr using maceration and sonication extraction methods. Journal Pharmaceutical Sciences, 5(1), 53-63. https://doi.org/10.24252/djps.v5i1.29317

Rosumeck, S., Nast, A., Dressler, C., 2018. Ivermectin and permethrin for treating scabies. Cochrane Database Syst. Rev, 4. https://doi.org/10.1002/14651858.CD012994

Sawitri, D., Yuningsih, Y., 2020. Ekstrak minyak kelapa daun gamal (Gliricidia sepium) sebagai akarisida botani untuk skabies pada kambing. Jurnal Veteriner, 21(4), 617-628. doi:10.19087/jveteriner.2020.21.4.617

Surahmaida, Umarudin, Rani, A.W., Dewi, N.C., 2021. Phytochemical screening of secondary metabolite compounds methanol extract of jatropha curcas leaf with GCMS. Journal of Pharmacy and Science, 6(1), 25-30. https://doi.org/10.53342/pharmasci.v6i1.202

Wu, J., Zhang, J., 2020. Research and development of natural vegetable insulating oil based on Jatropha curcas seed oil. Energies, 13(17), 1-12. https://doi.org/10.3390/en13174319s




DOI: https://doi.org/10.17969/agripet.v25i1.43371

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