ORIGINAL ARTICLE: CLINICAL PROFILE AND EPIDEMIOLOGICAL ASPECTS OF DIPHTHERIA CASES IN RUANG ISOLASI KHUSUS RSUD DR SOETOMO FROM JANUARY UNTIL DECEMBER 2015

Andi Airina Binti A Agus, Dominicus Husada, Pudji Lestari

Abstract


Abstract. Background Diphtheria is a vaccine-preventable disease and is eradicated mostly in developed countries. But the prevalence of diphtheria cases still remains endemic in developing countries such as Indonesia, mainly in East Java. Purpose: To study the clinical profile and epidemiological aspects of diphtheria cases admitted in Ruang Isolasi Khusus RSUD Dr. Soetomo in 2015. Method: This research is a hospital-based, cross-sectional study. The samples are all patients admitted in Ruang Isolasi Khusus RSUD Dr Soetomo with the diagnosis of diphtheria in 2015. Results: There were 23 diphtheria cases reported in Ruang Isolasi Khusus RSUD Dr. Soetomo in 2015. The most prevalent age group was 6 until 10 years old (56.52%) and the most common gender was male (57%). Most of the patients came from a non-endemic area (82.61%) and most of them are not fully vaccinated (73.91%). There are more unknowledgeable mothers (91%) about DPT immunization. The most prevalent clinical manifestations are fever, dysphagia and pseudomembrane (100%). Tonsillar diphtheria (86.96%) was the most prevalent type of diphtheria presented. There were no complications and mortality reported and the main managements used were isolation (100%), antibiotics (100%) and anti diphteria serum (82.61%). Conclusion: There is an age shift in the occurrence of diphtheria to 6 until 10 years of age. The immunization coverage especially the booster dose is still low among the patients. Less knowledge about DPT immunization contributes to low childhood immunization coverage. No complications and mortality reported.


Keywords


diptheria, re-emerging, anti diphtheria serum, DPT immunization

References


References

Dittmann, S., Wharton, M., Vitek, C., Ciotti, M., Galazka, A., Guichard, S., … Trostle, M. (2000). Successful Control of Epidemic Diphtheria in the States of the Former Union of Soviet Socialist Republics: Lessons Learned. The Journal of Infectious Diseases, 181(s1), S10–S22. doi:10.1086/315534

CDC. 2015. Epidemiology and Prevention of Vaccine-Preventable Diseases. Vol. 13:107-114

G.V., B., Chebbi, P., & Joshi, S. (2016). Resurgence of diphtheria: clinical profile and outcome - a retrospective observational study. International Journal of Contemporary Pediatrics, 60–63. doi:10.18203/2349-3291.ijcp20160058

Galazka, A. (2000). The Changing Epidemiology of Diphtheria in the Vaccine Era. The Journal of Infectious Diseases, 181(s1), S2–S9. doi:10.1086/315533

Kamau, N., & Esamai, F. O. (2001). Determinants of immunization coverage among children in Mathare Valley, Nairobi. East African Medical Journal, 78(11). doi:10.4314/eamj.v78i11.8949

Luthfi M. M., Sugihartiningsih. 2014. Hubungan Tingkat Pengetahuan Ibu Tentang Imunisasi Dengan Kelengkapan Imunisasi Dasar. Universitas Muhammadiyah. Semarang.

Arifin, I. F., & Prasasti, C. I. (2017). Factors That Related With Diptheria Cases of Children in Bangkalan Health Centers in 2016. Jurnal Berkala Epidemiologi, 5(1), 26. doi:10.20473/jbe.v5i1.2017.26-36

Kementerian Kesehatan Republik Indonesia, 2015. Profil Kesehatan Indonesia tahun 2014, Kemenkes RI. Jakarta.

Phalkey, R. K., Bhosale, R. V., Joshi, A. P., Wakchoure, S. S., Tambe, M. P., Awate, P., & Marx, M. (2013). Preventing the preventable through effective surveillance: the case of diphtheria in a rural district of Maharashtra, India. BMC Public Health, 13(1). doi:10.1186/1471-2458-13-317

Shrivastwa, N., Gillespie, B. W., Kolenic, G. E., Lepkowski, J. M., & Boulton, M. L. (2015). Predictors of Vaccination in India for Children Aged 12–36 Months. American Journal of Preventive Medicine, 49(6), S435–S444.

doi:10.1016/j.amepre.2015.05.008

M., M., & M., R. (2014). Diphtheria in Andhra Pradesh–a clinical-epidemiological study. International Journal of Infectious Diseases, 19, 74–78. doi:10.1016/j.ijid.2013.10.017

Izza, N., & Soenarnatalina, S. (2015). Analysis of Spatial Data of Diphtheria Disease in East Java Province during the year 2010 and 2011. Buletin Penelitian Sistem Kesehatan, 18(2). doi:10.22435/hsr.v18i2.4353.211-219

Primayani D. 2016. Faktor Risiko Kejadian Difteri Pada Anak di Jawa Timur Tahun 2011 – 2015. Karya Ilmiah Akhir Program Pendidikan Dokter Spesialis I Ilmu Kesehatan Anak. Surabaya, Universitas Airlangga.

Indriasih E., Ariningrum R. 2011. Identifikasi Wilayah dengan Permasalahan Kesehatan Anak Balita di Provinsi Jawa Timur. Buletin Penelitian Sistem Kesehatan.Vol. 14(1):30-39.

Kementerian Kesehatan Republik Indonesia, 2015. Profil Kesehatan Indonesia tahun 2014, Kemenkes RI. Jakarta.


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DOI: 10.24815/jks.v19i1.18048

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