Karakteristik Klinis dan Histopatologi Karsinoma Nasofaring di RSPAL Dr. Ramelan, Surabaya
Abstract
Kata kunci: RSPAL Dr. Ramelan, karsinoma nasofaring, gejala, stadium klinis, WHO subtipe
Abstract. Nasopharyngeal Carcinoma (NPC) is the fourth most common head and neck cancers in Indonesia. However, a detailed study of this malignancy has not been conducted at Dr. Ramelan Naval Central Hospital (RSPAL Dr. Ramelan), Surabaya. This descriptive study used medical records of newly diagnosed NPC patients registered in the ENT outpatient clinic at RSPAL Dr. Ramelan between October – December 2020. Patient’s characteristics including presented symptoms, clinical staging and histopathological subtypes were recorded and evaluated. Of the 22 NPC patients, two-thirds were males, more than half presented with the chief complaint of a lump in their neck, and almost all patients were already in the advanced stage. Histopathological findings showed the WHO III subtype was the commonest form of NPC. Therefore, early diagnosis is an important strategy to improves cancer therapy by providing the best care at the earliest possible stage.
Keywords: RSPAL Dr. Ramelan, nasopharyngeal carcinoma, symptoms, clinical staging, WHO subtype
Keywords
References
Rennatha A and Romdhoni AC, Etiopatogenesis karsinoma nasofaring. In: Romdhoni AC, Bunga rampai karsinoma nasofaring diagnosis dan terapi terkini. Airlangga University Press. 2021: (1); p.1-4
Adham M, et al., Nasopharyngeal carcinoma in indonesia: Epidemiology, incidence, signs, and symptoms at presentation. Chin. J. Cancer. 2012: 31; p. 185–96
Faiza S, Rahman S and Asri A, Karakteristik Klinis dan Patologis Karsinoma Nasofaring di Bagian THT-KL RSUP Dr. M. Djamil Padang. J. Kesehat. Andalas. 2016: 5; p.90-6
Shoffi MN., Hubungan ekspresi epstein barr virus encoded small rna dengan jenis histopatologi karsinoma nasofaring. Dalam: Karya akhir untuk memperoleh ijazah keahlian ilmu kesehatan telinga hidung tenggorok bedah kepala dan leher, Departemen/SMF Ilmu Kesehatan THT-KL FK UNAIR/ RSUD Dr. Soetomo Surabaya. 2016
Mulyarjo, Diagnosis dan penatalaksanaan karsinoma nasofaring. Dalam: (Mulyarjo, Soedjak S. Wisnubroto, Harmadji S. Hasanusi R. Artono ed). Naskah lengkap Pendidikan Kedokteran Berkelanjutan III Ilmu Kesehatan THT-KL, Surabaya: Laboratorium/SMF Ilmu Penyakit THT-KL FK UNAIR/ RSUD Dr. Soetomo Surabaya, 2002: hal 38-48
Handayani R. Afriani DY. & Madani DZ., Prevalence of Nasopharyngeal Carcinoma Patients in Departement of Orl-Hns Hasan Sadikin General Hospital 2010 -2017. Int. J. Nasopharyngeal Carcinoma. 2020: 2; p.1–3.
Romdhoni AC. et al., Clinical presentation of nasopharyngeal Carcinoma in East Java, Indonesia. Pakistan J. Med. Heal. Sci. 2020: 14; p. 942–6.
Xie SH. Yu IT. sunTse LA. Au JSK. & Lau JSM., Occupational risk factors for nasopharyngeal carcinoma in Hong Kong Chinese: a case-referent study. Int. Arch. Occup. Environ. Health. 2017: 90; p.443–9.
Brennan B., Nasopharyngeal carcinoma. Orphanet J. Rare Dis. 2006:1; p.1–5.
Naomi, S. M., Dewi, Y. A. & Agustina, H. Association between Histopathological Grading and Clinical Staging in Nasopharyngeal Carcinoma. J. Med. Heal., 2018: 2; p. 730-7
Tang, S. Q. et al. The evolution of the nasopharyngeal carcinoma staging system over a 10-year period: implications for future revisions. Chin. Med. J. (Engl). 2020: 133; p.2044–53
DOI: 10.24815/jks.v22i3.21689
Refbacks
- There are currently no refbacks.