PUASA RAMADHAN DAN PENGARUHNYA TERHADAP PROGRESIFITAS PENYAKIT GINJAL KRONIK

Abdullah Abdullah, Desi Salwani, Muhsin Muhsin, Andri Baftahul Khairi, Maimun Syukri

Abstract


Bulan Ramadhan merupakan bulan suci umat Islam dimana pada bulan ini seluruh umat Islam diwajibkan untuk berpuasa selama satu bulan penuh, mulai dari terbit fajar hingga tenggelam matahari. Pengaruh puasa Ramadhan terhadap fisiologis dan biokimia tubuh telah banyak dipelajari dengan hasil yang berbeda-beda. Banyak penelitian menunjukkan puasa Ramadhan dapat ditoleransi dengan aman pada orang sehat dan memberikan efek yang menguntungkan dalam hal regulasi tekanan darah, kadar lipid darah, stres oksidatif, sensitivitas insulin, dan penyakit jantung kronis jika dilakukan dengan benar. Ada banyak kontroversi mengenai puasa Ramadhan untuk penderita Penyakit Ginjal Kronik (PGK) terutama apakah puasa tersebut memperbaiki indikator fungsi ginjal atau malah sebaliknya. Terdapat juga banyak kekhawatiran tentang dampak dehidrasi dan efek hipoperfusi ginjal selama puasa Ramadhan terhadap penderita PGK. Tinjauan kepustakaan ini memberikan bukti-bukti terbaru tentang pengaruh puasa Ramadhan terhadap progresifitas PGK, baik pada penderita predialisis, yang sedang menjalani dialisis, maupun yang telah menjalani transplantasi ginjal.


Keywords


Puasa Ramadhan, Penyakit Ginjal Kronik, Fungsi Ginjal, dialisis, transplantasi ginjal

References


Hall JE, Guyton AC. The Urinary System: Functional Anatomy and Urine Formation by the Kidneys. In: Gauyton and Hall Text Book of Medical Physiology. Thirteen. Mississippi: Elsivier; 2016. p. 323–34.

Sherwood L. Fisiologi ginjal. In: Fisiologi Manusia dari Sel ke Sel. Edisi 8. Jakarta: EGC; 2013.

Foundation NK. K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification and Stratification. Am J Kidney Dis. 2002;39(1):1–266.

Suwitra K. Penyakit Ginjal Kronik. In: Buku Ajar Ilmu Penyakit Dalam Edisi VI. VI. Jakarta: Interna Publishing; 2015. p. 2159–65.

Emami-Naini A, Roomizadeh P, Baradaran A, Abedini A, Abtahi M. Ramadan fasting and patients with renal diseases: A mini review of the literature. J Res Med Sci. 2013;18(8):711–6.

Dogan I, Eser B, Kayadibi H. The effect of Ramadan fasting on renal functions in patients with chronic kidney disease. Turkish J Biochem [Internet]. 2019 Apr 24;44(2):189–96. Available from: https://www.degruyter.com/document/doi/10.1515/tjb-2018-0373/html

Hassan S, Hassan F, Abbas N, Hassan K, Khatib N, Edgim R, et al. Does Ramadan Fasting Affect Hydration Status and Kidney Function in CKD Patients? Ann Nutr Metab [Internet]. 2018;72(3):241–7. Available from: https://www.karger.com/DOI/10.1159/000486799

Khazneh E, Qaddumi J, Hamdan Z, Qudaimat F, Sbitany A, Jebrin K, et al. The effects of Ramadan fasting on clinical and biochemical markers among hemodialysis patients: A prospective cohort study. PLoS One. 2019;14(6):1–11.

Bargman JM, Skorecki KL. Chronic Kidney Disease. In: Kasper M, Fauci AS, Hauser SL, Longo DL, Jameson JL, Loscalzo J, editors. Harrison’s Principles of Internal Medicine. 20th ed. New York, NY: McGraw-Hill Education; 2018. p. 2111–21.

Mitra PK, Tasker PRW, Ell MS. Chronic kidney disease. Vol. 97, Praxis. 2008. 947–948 p.

Zhong J, Yang XH, Fogo AB. Mechanism and Treatment of Renal Fibrosis A perspective on chronic kidney disease progression. 2021;37232.

Balasubramanian S. Progression of chronic kidney disease : Mechanisms and interventions in retardation. Apollo Med. 2013;10(1):19–28.

Düsing R. Risk Factors in the Progression of Chronic Kidney Disease. 2006;

N.L. B. Ramadan fasting and chronic kidney disease: A systematic review. J Res Med Sci. 2014;19(7):665–76.

Ahmad S, Chowdhury TA. Fasting during Ramadan in people with chronic kidney disease: a review of the literature. Ther Adv Endocrinol Metab [Internet]. 2019 Jan 14;10:204201881988901. Available from: https://pubmed.ncbi.nlm.nih.gov/31798822

Berbari AE, Daouk NA, Mallat SG, Jurjus AR. Ramadan Fasting in Health and Disease. In: Special Issues in Hypertension. Milan: Springer Verlag Italia; 2012. p. 331–46.

El-Wakil HS, Desoky I, Notfy N, Adam AG. Fasting the month of Ramadan by Muslims: Could it be injurious to their kidneys? Saudi J Kidney Dis Transpl. 2007;18(3):349–54.

Bakhit A, Kurdi A, Wadera J, Alsuwaida A. Effects of Ramadan fasting on moderate to severe chronic kidney disease. A prospective observational study. Saudi Med J [Internet]. 2017 Jan 1;38(1):48–52. Available from: https://pubmed.ncbi.nlm.nih.gov/28042630

Bernieh B, Al Hakim M, Boobes Y, Abu Zidan F. Fasting Ramadan in chronic kidney disease patients: Clinical and biochemical effects. Saudi J Kidney Dis Transplant [Internet]. 2010 Sep 1;21(5):898–902. Available from: http://www.sjkdt.org/article.asp?issn=1319-2442

Wakeel JS. Kidney function and metabolic profile of chronic kidney disease and hemodialysis patients during Ramadan fasting. Iran J Kidney Dis. 2014;8(1):321–8.

Rafiu MO, Ahmed SD, Aigbiremolen AO, Alili IB, Akhideno PE, Erameh CO, et al. Intradialytic complications : a poor prognostic factor among patients with lassa fever with acute kidney injury undergoing hemodialysis. J Egypt Soc Nephrol Transplant. 2019;19(4):118–23.

Wan Md Adnan WAH, Zaharan NL, Wong MH, Lim SK. The effects of intermittent fasting during the month of Ramadan in chronic haemodialysis patients in a tropical climate country. PLoS One. 2014;9(12):1–12.

Einollahi B, Lessan-Pezeshki M, Simforoosh N, Nafar M, Pour-Reza-Gholi F, Firouzan A, et al. Impact of ramadan fasting on renal allograft function. Transplant Proc. 2005;37(7):3004–5.

Said T, Nampoory MRN, Haleem MA, Nair MP, Johny K V., Samhan M, et al. Ramadan fast in kidney transplant recipients: A prospective comparative study. Transplant Proc. 2003;35(7):2614–6.

Ghalib M, Qureshi J, Tamim H, Ghamdi G, Flaiw A, Hejaili F, et al. Does repeated Ramadan fasting adversely affect kidney function in renal transplant patients? Transplantation. 2008;85(1):141–4.

Einollahi B, Lessan-Pezeshki M, Pourfarziani V, Aghdam B, Rouzbeh J, Ghadiani MH, et al. Ramadan fasting in kidney transplant recipients with normal renal function and with mild-to-moderate renal dysfunction. Int Urol Nephrol. 2009;41(2):417–22.


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DOI: 10.24815/jks.v21i3.23754

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