Acute pancreatitis with peritoneal fat necrosis with atypical clinical symptoms

Afira Febriani Surya Wijaya, Ardyarini Dyah Savitri

Abstract


Introduction: Acute pancreatitis (AP) is characterized by severe and persistent abdominal pain due to pancreas inflammation. This study aims to describe the diagnostic and therapeutic steps chosen to treat patients with acute pancreatitis due to cholelithiasis who have experienced necrosis of the peritoneal fat tissue with atypical symptoms using a simple examination.

Case Presentation: The patient complained of abdominal pain in the left hypochondrium. The pain was described as intermittent and sharp, without spreading, and is accompanied by nausea and vomiting, persisting for the past two weeks. The following day, the abdominal pain became more severe and persistent, especially with changes in position. Abdominal examination shows distended, defensive muscles and decreased bowel sounds. The ultrasound examination results showed that there were gallstones in the neck bladder measuring 5 mm and minimal fluid between the intestines and McBurney. Abdominal plain radiograph (BOF-LLD) results provide a ground glass appearance in the abdominal cavity. The patient underwent exploratory laparotomy, antibiotics and supportive therapy. The patient was discharged on day 9.

Discussion: Computer tomography can be used in uncertain diagnosis, and ultrasonography (USG) cannot visualize AP. However, in cases of signs of peritonitis, surgery can be used for therapy and to confirm the diagnosis.

Conclusion: Signs of peritonitis increase the urgency in this patient; prompt exploratory surgery is performed to remove the focus of infection and help confirm the diagnosis. In addition to administering antibiotics and supportive therapy, surgery can provide satisfactory results


Keywords


Gallstones, Acute Pancreatitis, Peritonitis

References


Alkareemy, E. A. R., Ahmed, L. A.-W., El-Masry, M. A., Habib, H. A., & Mustafa, M. H. (2020). Etiology, clinical characteristics, and outcomes of acute pancreatitis in patients at Assiut University Hospital. The Egyptian Journal of Internal Medicine, 32(1), 24.

Anastasiu, M., Şurlin, V., & Beuran, M. (2021). The Management of the Open Abdomen—A Literature Review. Chirurgia, 116(6 suppl), 645.

Boumitri, C., Brown, E., & Kahaleh, M. (2017). Necrotizing Pancreatitis: Current Management and Therapies. Clinical Endoscopy, 50(4), 357–365.

Boxhoorn, L., Voermans, R. P., Bouwense, S. A., Bruno, M. J., Verdonk, R. C., Boermeester, M. A., Santvoort, H. C. van, & Besselink, M. G. (2020). Acute pancreatitis. The Lancet, 396(10252), 726–734.

Burrowes, D. P., Choi, H. H., Rodgers, S. K., Fetzer, D. T., & Kamaya, A. (2020). Utility of ultrasound in acute pancreatitis. Abdominal Radiology (New York), 45(5), 1253–1264.

Chan, K. S., & Shelat, V. G. (2022). Diagnosis, severity stratification and management of adult acute pancreatitis–current evidence and controversies. World Journal of Gastrointestinal Surgery, 14(11), 1179–1197.

Chatila, A. T., Bilal, M., & Guturu, P. (2019). Evaluation and management of acute pancreatitis. World Journal of Clinical Cases, 7(9), 1006–1020.

Chua, T. Y., Walsh, R. M., Baker, M. E., & Stevens, T. (2017). Necrotizing pancreatitis: Diagnose, treat, consult. Cleveland Clinic Journal of Medicine, 84(8), 639–648.

Clements, T. W., Tolonen, M., Ball, C. G., & Kirkpatrick, A. W. (2021). Secondary Peritonitis and Intra-Abdominal Sepsis: An Increasingly Global Disease in Search of Better Systemic Therapies. Scandinavian Journal of Surgery, 110(2), 139–149.

D’AMATA, G., REGA, M., VIOLA, V., BOVE, V., SIMEONE, P., & BAIANO, G. (2016). Chyloperitoneum associated with idiopathic pancreatitis: Case report and review of the literature. Il Giornale Di Chirurgia, 37(4), 167–170.

Devos, H., Goethals, L., Belsack, D., Brucker, Y., Allemeersch, G.-J., Ilsen, B., Vandenbroucke, F., & Mey, J. (2020). Fat misbehaving in the abdominal cavity: A pictorial essay. Polish Journal of Radiology, 85(1), 32–38.

Farzad Vaghef Davari & Hadi Ahmadi Amoli. (2019). Approach to Acute Abdominal Pain: Practical Algorithms. Advanced Journal of Emergency Medicine.

Goodchild, G., Chouhan, M., & Johnson, G. J. (2019). Practical guide to the management of acute pancreatitis. Frontline Gastroenterology, 10(3), 292–299.

Greenberg, J., & Hsu, J. (2016). Clinical practice guideline: Management of acute pancreatitis. Canadian Journal of Surgery, 59.

Huang, Y., & Badurdeen, D. S. (2023). Acute Pancreatitis Review. The Turkish Journal of Gastroenterology, 34(8), 795–801.

Kundumadam, S., Fogel, E. L., & Gromski, M. A. (2021). Gallstone pancreatitis: General clinical approach and the role of endoscopic retrograde cholangiopancreatography. The Korean Journal of Internal Medicine, 36(1), 25–31. https://doi.org/10.3904/kjim.2020.537

Lee, P. J., & Papachristou, G. (2019). New Insights into Acute Pancreatitis. Gastroenterology & Hepatology.

Li Yousheng. (2021). Rational use of antibiotics in severe acute pancreatitis: Controversy and progress. Chinese Medical Journal, 101(30), Article 30.

McPherson, S. J., O’Reilly, D. A., Sinclair, M. T., & Smith, N. (2017). The use of imaging in acute pancreatitis in United Kingdom hospitals: Findings from a national quality of care study. The British Journal of Radiology, 90(1080), 20170224.

Nadhem, O., & Salh, O. (2017). Acute Pancreatitis: An Atypical Presentation. Case Reports in Gastroenterology, 11(2), 359.

Ouyang, G., Pan, G., Liu, Q., Wu, Y., Liu, Z., Lu, W., Li, S., Zhou, Z., & Wen, Y. (2020). The global, regional, and national burden of pancreatitis in 195 countries and territories, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017. BMC Medicine, 18, 388.

Rahman, Md. S., Banna, H. U., Hasan, Md. N., & Jumman, M. (2020). Advantage of laparoscopic peritoneal toileting in acute peritonitis with unclear etiology: A case report with inspiring outcome (with video). International Journal of Surgery Case Reports, 72, 285–289.

Ross, J. T., & Matthay, M. A. (2018). Secondary Peritonitis: Principles of Diagnosis and Intervention. BMJ.

Shah, H., Nisar, N., Hassan, A., & Butt, S. (2022). Association between maternal chronic apical periodontitis (CAP) and low birth weight preterm birth (LBWPT). Journal of the Pakistan Medical Association, 72(3), 436–439. Scopus.

Siregar, G. A., & Siregar, G. P. (2019). Management of Severe Acute Pancreatitis. Open Access Macedonian Journal of Medical Sciences, 7(19), 3319–3323.

Szatmary, P., Grammatikopoulos, T., Cai, W., Huang, W., Mukherjee, R., Halloran, C., Beyer, G., & Sutton, R. (2022). Acute Pancreatitis: Diagnosis and Treatment. Drugs, 82(12), 1251–1276.

Vengadakrishnan, K., & Koushik, A. K. (2015). A study of the clinical profile of acute pancreatitis and its correlation with severity indices. International Journal of Health Sciences, 9(4), 410–417.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682595/

Walkowska, J., Zielinska, N., Tubbs, R. S., Podgórski, M., Dłubek-Ruxer, J., & Olewnik, Ł. (2022). Diagnosis and Treatment of Acute Pancreatitis. Diagnostics, 12(8), 1974.

Zerem, E. (2014). Treatment of severe acute pancreatitis and its complications. World Journal of Gastroenterology: WJG, 20(38), 13879–13892.


Full Text: PDF

DOI: 10.24815/jks.v24i1.34263

Refbacks

  • There are currently no refbacks.