Candida peritonitis on peritoneal dialysis: case report

Desi Salwani Hasan, Abdullah Abdullah, Merizka Adelina


Background: Chronic renal failure patients who utilize peritoneal dialysis often develop peritonitis. Peritonitis can have several causes, including Candida Parapsilosis. The mortality rate and peritoneal dialysis failure rate will rise with inadequate care.

Case illustration: A 46-year-old man has been experienced nausea and abdominal pain for a week. Peritoneal dialysis fluid becomes cloudy. The patient was receiving peritoneal dialysis for four years due to end-stage renal failure. Leg edema was seen, but the abdominal physical examination was normal. The results of the laboratory analysis for potassium, leukocytes, hemoglobin, and albumin were 2.8 g/dL, 4.5 mmol/L, 18800 103/mm, and 8 g/dL, respectively. The existence of Candida parapsilosis was discovered by peritoneal dialysis fluid culture. Peritonitis caused by Candida is the diagnosis in this instance. The patient received intraperitoneal injections of ceftriaxone 1 gram every 24 hours, fluconazole 200 mg, and Dianel 1.5% 2000 cc every six hours. After three days, the peritoneal dialysis fluid cleared up and the complaints of abdominal pain subsided, allowing Tenchoff PD to be maintained. Therapy sessions could last up to 14 days..

Discussion: The most frequent complaint of fungal peritonitis is abdominal pain. Peritoneal dialysis fluid culture is the usual diagnostic method. Leukocystosis in this case required antibiotics along with the antifungal medication Fluconazole 200 mg every 24 hours for 14 days.

Conclusion : Antifungals can prevent tenchoff failure and are helpful in cases of Candida-related peritonitis.


Candida; peritonitis; and peritoneal dialysis



Agudo, R. G., & García-Martos, P. (2009). Clinical and microbiological aspects of fungal peritonitis in peritoneal dialysis. Nefrologia, 29(6), 506–517.

Auricchio, S., Giovenzana, M. E., Pozzi, M., Galassi, A., Santorelli, G., Dozio, B., & Scanziani, R. (2018). Fungal peritonitis in peritoneal dialysis: a 34-year single centre evaluation. Clinical Kidney Journal, 11(6), 874–880.

Chang, T. I., Kim, H. W., Park, J. T., Lee, D. H., Lee, J. H., Yoo, T. H., & Kang, S. W. (2011). Early catheter removal improves patient survival in peritoneal dialysis patients with fungal peritonitis: Results of ninety-four episodes of fungal peritonitis at a single center. Peritoneal Dialysis International, 31(1), 60–66.

Giacobino, J., Montelli, A. C., Barretti, P., Bruder-Nascimento, A., Caramori, J. T., Barbosa, L., & Bagagli, E. (2016). Fungal peritonitis in patients undergoing peritoneal dialysis (PD) in Brazil: molecular identification, biofilm production and antifungal susceptibility of the agents. Medical Mycology, 54(7), 725–732.

Goldie, S. J., Kiernan-Troidle, L., Torres, C., Gorban-Brennan, N., Dunne, D., Kliger, A. S., & Finkelstein, F. O. (1996). Fungal peritonitis in a large chronic peritoneal dialysis population: A report of 55 episodes. American Journal of Kidney Diseases, 28(1), 86–91.

Guimarães Rosa, N., Silva, S., Lopes, J. A., Branco, P., De Almeida, E., Ribeiro, C., Abreu, F., Barbas, J., & Martins Prata, M. (2007). Fungal peritonitis in peritoneal dialysis patients: Is previous antibiotic therapy an essential condition? Mycoses, 50(1), 79–81.

Li, P. K. T., Chow, K. M., Cho, Y., Fan, S., Figueiredo, A. E., Harris, T., Kanjanabuch, T., Kim, Y. L., Madero, M., Malyszko, J., Mehrotra, R., Okpechi, I. G., Perl, J., Piraino, B., Runnegar, N., Teitelbaum, I., Wong, J. K. W., Yu, X., & Johnson, D. W. (2022). ISPD peritonitis guideline recommendations: 2022 update on prevention and treatment. Peritoneal Dialysis International, 42(2), 110–153.

Matuszkiewicz-Rowinska, J. (2009). Update on fungal peritonitis and its treatment. Peritoneal Dialysis International, 29(SUPPL. 2), 161–165.

Miles, R., Hawley, C. M., McDonald, S. P., Brown, F. G., Rosman, J. B., Wiggins, K. J., Bannister, K. M., & Johnson, D. W. (2009). Predictors and outcomes of fungal peritonitis in peritoneal dialysis patients. Kidney International, 76(6), 622–628.

Nadeau-Fredette, A. C., & Bargman, J. M. (2015). Characteristics and outcomes of fungal peritonitis in a modern North American cohort. Peritoneal Dialysis International, 35(1), 78–84.

Prasad Narayan, G. A. (2005). Fungal peritonitis in peritoneal dialysis patient. Perit Dial Int, 25(3), 207–222.

Wang, A. Y. M., Yu, A. W. Y., Li, P. K. T., Lam, P. K. W., Leung, C. B., Lai, K. N., & Lui, S. F. (2000). Factors predicting outcome of fungal peritonitis in peritoneal dialysis: Analysis of a 9-year experience of fungal peritonitis in a single center. American Journal of Kidney Diseases, 36(6), 1183–1192.

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DOI: 10.24815/jks.v23i3.35184


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