Vitiligo Profile at Dr. Zainoel Abidin Hospital, Banda Aceh: retrospective study
Abstract
Introduction: Vitiligo is a skin condition characterized by a lack of or damage to melanocytes, which results in depigmented lesions on the skin and mucosa.
Objective: To describe the patients’ profile of vitiligo at the Dermatology and Venereology Clinic of dr. Zainoel Abidin General (RSUDZA) Hospital Banda Aceh.
Methods: A retrospective observational descriptive study on vitiligo patients who were treated at the Dermatology and Venereology Clinic of RSUDZA Banda Aceh for the period January 2017 to June 2023.
Results: A 6-year observation yielded a total of 2135 vitiligo patients. The year with the most vitiligo visitors was 202218 (5443 patients). Most cases were in women (536.2%), the majority of the age group >55 years (223%), age of onset 46-55<17 years (16%), and only 21% had a family history of vitiligo. The most prevalent dermatological conditions were acrofacial vitiligo (24%), multiple lesions (838%), nummular lesions (289%), and the presence of head and neck lesions (201%). Topical steroids were given to the patient as topical therapy (976%). A total of 31% of patients had oral medication, while 294% received phototherapy.
Keywords
References
An, R., Li, D., Dong, Y., She, Q., Zhou, T., Nie, X., Pan, R., & Deng, Y. (2021). Methylcobalamin Protects Melanocytes from H2O2-Induced Oxidative Stress by Activating the Nrf2/HO-1 Pathway. Drug Design, Development and Therapy, 15(August).
Bergqvist, C., & Ezzedine, K. (2020). Vitiligo: A Review. Dermatology, 236, 571–592. https://doi.org/10.1159/000506103
Bergqvist, C., & Ezzedine, K. (2021). Vitiligo: A focus on pathogenesis and its therapeutic implications. Journal of Dermatology, 48(3), 252–270. https://doi.org/10.1111/1346-8138.15743
Chauhan, P. S., Sharma, H., Dhattarwal, N., Mahajan, V. K., Mehta, K. S., Sharma, A., Sharma, R., Verma, Y. R., & Chandel, M. (2020). Characteristics of Vitiligo in Children and Adolescents. Skinmed, 18(5), 278–285.
Diana, R., & Mulianto, N. (2018). Modalitas Terapi Topikal Vitiligo. Cermin Dunia Kedokteran, 45(7), 508–513.
Gandhi, K., Ezzedine, K., Anastassopoulos, K. P., Patel, R., Sikirica, V., Daniel, S. R., Napatalung, L., Yamaguchi, Y., Baik, R., & Pandya, A. G. (2022). Prevalence of Vitiligo among Adults in the United States. JAMA Dermatology, 158(1), 43–50. https://doi.org/10.1001/jamadermatol.2021.4724
Ghosh, S. (2020). Chemical Vitiligo: A Subset of Vitiligo. Indian Journal of Dermatology, 65(6), 443–449.
Gupta, V. (2019). Clinical and Histopathological Study in Vitiligo Patients. Journal of Medical Science And Clinical Research, 7(3), 1457–1463. https://doi.org/10.18535/jmscr/v7i3.243
Henning, S. W., Jaishankar, D., Barse, L. W., Dellacecca, E. R., Lancki, N., Webb, K., Janusek, L., Mathews, H. L., Price, R. N., & Caroline Le Poole, I. (2020). The relationship between stress and vitiligo: Evaluating perceived stress and electronic medical record data. PLoS ONE, 15(1), 1–14. https://doi.org/10.1371/journal.pone.0227909
Hidayatullah. (2020). Profil Pasien Vitiligo Di Poli Kulit Kelamin Rumah Sakit Umum Pusat Sanglah. Jurnal Medika Udayana, Vol 10 No(2), 9–12.
Kang, S., Amagai, M., Bruckner, A. L., Enk, A. H., Margolis, D. J., McMichael, A. J., & Orringer, J. S. (2019). Fitzpatrick’s Dermatology 9th Edition Vol. I. McGraw-Hill Education.
Lei, T., Xu, A., Gao, T., He, L., Gu, H., Li, M., Li, T.-N., Li, C.-Y., Lin, T., Mu, K.-H., Tu, C.-X., Wen, H., Wu, J.-Y., Zhang, J.-L., & Zhen, Z.-Z. (2021). Consensus on the Diagnosis and Treatment of Vitiligo in China (2021 Revision). International Journal of Dermatology and Venereology, 4, 1. https://doi.org/10.1097/JD9.0000000000000151
Malik, S., & Cohen, P. R. (2021). Vitiligo-Associated Autoimmune Disorders: A Woman With Vitiligo and Incipient Hypothyroidism. Cureus, 13(10), e19164. https://doi.org/10.7759/cureus.19164
Mirnezami, M., & Rahimi, H. (2018). Serum Zinc Level in Vitiligo: A Case-control study. Indian Journal of Dermatology, 63(3), 227–230.
Mohr, N., Petersen, J., Kirsten, N., & Augustin, M. (2021). Epidemiology of Vitiligo – A Dual Population-Based Approach. Clinical Epidemiology, 13, 373–382.
Passeron, T., Ortonne, J.-P., Kumarasinghe, P., & Taïeb, A. (2019). Vitiligo/nonsegmental Vitiligo Including Acrofacial and Universalis. Vitiligo, 41–51. https://doi.org/10.1007/978-3-319-62960-5_5
Rahmayanti, N. D., & Rahmadewi. (2016). Studi Retrospektif: Profil Pasien Baru Vitiligo. E-Journal Unair, 52–58.
Sani, S., Zare, A. G., & Radmehree, A. (2019). Zinc, Vitamin D, and TSH Levels in Patients with Vitiligo. Erciyes Medical Journal, 41(2).
Singh, N., & Gera, V. (2019). Evaluation of Zinc Levels in Patients with Vitiligo: A Clinical study. Journal of Advanced Medical and Dental Sciences Research, 7(1), 156–158. https://doi.org/10.21276/jamdsr
Thakur, V., Bishnoi, A., Vinay, K., Kumaran, S. M., & Parsad, D. (2021). Vitiligo: Translational research and effective therapeutic strategies. Pigment Cell and Melanoma Research, 34, 814–826. https://doi.org/10.1111/pcmr.12974
Vachiramon, V., Onprasert, W., Harnchoowong, S., & Chanprapaph, K. (2017). Prevalence and Clinical Characteristics of Itch in Vitiligo and Its Clinical Significance. BioMed Research International, 2017(December 2016). https://doi.org/10.1155/2017/5617838
Wang, Y., Li, S., & Li, C. (2019). Perspectives of new advances in the pathogenesis of vitiligo: From oxidative stress to autoimmunity. Medical Science Monitor, 25, 1017–1023. https://doi.org/10.12659/MSM.914898
Yoon, S. J., Gianturco, S. L., Pavlech, L. L., Storm, K. D., Yuen, M. V., & Mattingly, A. N. (2020). Methylcobalamin: Summary Report.
DOI: 10.24815/jks.v24i3.38432
Refbacks
- There are currently no refbacks.