3. Efficacy of Jatropha (Jatropha curcas L) Cream sap Leucocytes in Inflammation Phase of Wound Healing

Mita Nasuha Risky, Triva Murtina Lubis, M. Nur Salim, Teuku Zahrial Helmi, Abdul Harris, Hennivanda Hennivanda, Dian Masyitha, Cut Dahlia Iskandar, Fitriani Fitriani, Abdul Hamzah, T. Fadrial Karmil

Abstract


This study aims to determine the efficacy of giving jatropha cream (Jatropha curcas L.) on the number of leukocytes in the inflammatory phase of wound healing in the mice’s skin. The method used is literature study research with qualitative techniques. The data used in this study comes from the result of studies that have been conducted and published in national or international online journals. References used are all research articles with data selection. The results of data analysis showed that the administration of jatropha cream (Jatropha curcas L.) was effective in limiting or inhibiting the accumulation of leukocytes in the area of inflammation and could stimulate the formation of new blood vessels (angiogenesis) in the inflammatory phase of wound healing of the mice’s skin. Based on these data it can be concluded that the efficacy of jatropha cream (Jatropha curcas L.) affects the number of leukocytes in the inflammatory phase of wound healing of mice's skin.


Keywords


Jatropha curcas; leucocites; wound healing; literature review

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References


Argamula, G. (2008). Aktivitas Sediaan Salep Ekstrak Batang Pohon Pisang Ambon (Musa paradisiacavar sapientum) dalam Proses Persembuhan Luka pada Mencit (Mus musculus albinus). Skripsi. Institut Pertanian Bogor, Bogor.

Balqis, U., Darmawi, Iskandar, C.D. dan Salim, M.N. (2018). Angiogenesis activity of Jatropha curcas L. latex in cream formulation on wound healing in mice. Veterinary World, 11(7): 939-943.

Dorland, W. (2006). Kamus Kedokteran Dorland. EGC, Jakarta.

Halim, R. M. (2014). Uji Efek Penyembuhan Luka Sayat Ekstrak Etanol Daun Kecombrang (Etlingera elatior) dalam Bentuk Sediaan Gel terhadap Kelinci (Oryctolagus cuniculus). Skripsi. Fakultas Ilmu Kesehatan UIN Alauddin, Makassar.

Hidayati, Salim, M.N., Balqis, U., Masyitha, D., Iskandar, C.D., Darmawi. dan Harris, A. (2019). Efficacy of jatropha (Jatropha curcas L) sap cream in inflammation phase of wound healing on mice skin. Jurnal Medika Veterinaria, 13(2): 232-238.

Hogiono dan Dogi. (1994). Peningkatan nilai tambah tanaman hortikultura yang berpotensi sebagai bahan dasar sintesis obat-obatan steroid. Jurnal Fakultas Matematika dan Ilmu Pengetahuan Alam. Universitas Airlangga Surabaya.

Igbinosa, O. O., E.O. Igbinosa, dan O.A. Aiyegoro. (2009). Antimicrobial activity and phytochemical screening of steam bark extracts from Jatropha curcas (Linn). African Journal of Pharmacy and Pharmacology, 3(2):58-62.

Izzaty, A., Nurdiana, D. dan Dewi, I.N.P. (2014). Ekstrak haruan (Channa striata) secara efektif menurunkan jumlah limfosit fase inflamasi dalam penyembuhan luka. Dentofasial, 13(3): 176-181.

Jayasekara, T.I., Stevenson, P.C., Belmain, S.R., Farman,

D.I. dan Hall, D.R. (2002). Identification of metylsalicylate as the principal volatile component in the methanol extract of root bark of Securidacalongi pedunculata Fers. J. Mass Spec, 37: 577-580.

Katzung, B.G. (2002). Farmakologi Dasar dan Klinik.

Penerbit Salemba, Jakarta.

Kee, J.L. dan Evelyn. (1996). Farmakologi; Pendekatan Proses Keperawatan. EGC, Jakarta.

Marsh, W.R., Irvin, C.G., Murphy, K.R., Behrens, B.L. dan Larsen, G.L. (1985). Increases in airway reactivity to histamine and inflammatory cells in bronchoalveolar lavage after the late asthmatic ressponse in an animal model. American Review of Respiratory Disease. 131(6): 875-879.

Marzoeki, D. (1993). Ilmu Bedah Luka dan Perawatannya.

Edisi I. Airlangga University Press, Surabaya.

Moher, D., Liberati, A., Tetzlaff, J. dan Altman, D.G. (2009). Academia and clinic annals of internal medicine preffered reporting items for systematic reviews and meta-analyses. Annuals of internal medicine, 151(4): 264-269.

Pavletic, M.M. (1992). Veterinary Emergency and Critical Care Medicine. Mosby Year Book, New York.

Puspitasari, R., Sunyoto dan Muchon, A. (2016). Uji efektifitas ekstrak lidah buaya (Aloe vera L.) terhadap penyembuhan luka sayat pada mencit jantan (Mus musculus) galur Swiis. Journal of Pharmacy Science, 3(1): 1-6.

Salim, M.N, Masyitha, D., Harris, A., Balqis, U., Iskandar, C.D., Hambal, M. dan Darmawi. (2018). Anti- inflammatory activity of Jatropha curcas Linn. latex in cream formulation on CD68 expression in mice skin wound. Veterinary World, 11(2): 99-103.

Salim, M.N., Silvia, M., Aliza, D., Masyitha, D., Iskandar, C.D., Rusli, Sugito, Hasan, M., Sabri, M. dan Harris, A. (2020). Efficacy of Jatropha curcas latex cream in the epithelialization phase of wound healing in mice skin. E3S Web of Conferences, 1-6.

Sari, S.A. (2013). Efektivitas Pemberian Vitamin C terhadap Aktivitas Osteoblas Pasca Pencabutan pada Tikus Wistar Jantan. Skripsi. Fakultas Kedokteran Gigi Universitas Jember, Jember.

Thomas, S., Rowe, H.N., Keats, J. dan Morgasn, R.J.H. (1997). The management of extravasation injury in neonates. World Wide Wound.




DOI: https://doi.org/10.21157/j.med.vet..v14i2.19092

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